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219339 Sigma-Aldrich

L-Ethionine

98%

Synonym: L-2-Amino-4-(ethylthio)butyric acid

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Properties

assay   98%
optical activity   [α]22/D +21.7°, c = 1 in 1 M HCl
mp   280 °C (dec.) (lit.)
SMILES string   CCSCC[C@H](N)C(O)=O
InChI   1S/C6H13NO2S/c1-2-10-4-3-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1
InChI key   GGLZPLKKBSSKCX-YFKPBYRVSA-N

Description

Packaging

5 g in glass bottle

Biochem/physiol Actions

An analog of methionine that interferes with the normal methylation of DNA and other methylation pathways, and induces pancreatic toxicity and liver cancer. However, in animal studies, it has also been shown to act synergistically with methionine-depletion to block the growth and metastasis of methionine-dependent tumors.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
ES6825300
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

replaced by

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Description

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E1260 L-Ethionine, ≥99% (TLC)

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