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220590 Sigma-Aldrich

Sodium orthovanadate

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Properties

mp   850-866 °C (lit.)
SMILES string   [Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O
InChI   1S/3Na.4O.V/q3*+1;;3*-1;
InChI key   IHIXIJGXTJIKRB-UHFFFAOYSA-N

Description

Application

Agent used in the study of diabetes.

Biochem/physiol Actions

Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
3
RTECS 
YW1120000
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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S6508 Sodium orthovanadate, ≥90% (titration)

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