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246557 Sigma-Aldrich

Tryptamine hydrochloride

99%

Synonym: 2-(3-Indolyl)ethylamine hydrochloride, 3-(2-Aminoethyl)indole hydrochloride

  • CAS Number 343-94-2

  • Empirical Formula (Hill Notation) C10H12N2 · HCl

  • Molecular Weight 196.68

  •  Beilstein/REAXYS Number 3568419

  •  EC Number 206-446-4

  •  MDL number MFCD00012682

  •  PubChem Substance ID 24278134

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Properties

Related Categories Alkaloid, Building Blocks, C10, Cell Biology, Chemical Synthesis,
InChI Key   KDFBGNBTTMPNIG-UHFFFAOYSA-N
assay   99%
mp   253-255 °C (lit.)
solubility   water: soluble 0.1 g/10 mL, clear to slightly hazy, colorless to yellow

Description

General description

The fluorescence property of tryptamine hydrochloride was studied in reverse micelles solution made with benzylhexadecyldimethylammonium chloride (BHDC) in benzene.

Application

Reactant for preparation of:
• Tryptamine derivatives as inhibitors against hepatitis B virus
• Carbamoyl epipodophyllotoxins as potential antitumor agents
• Anthranilic acid derivatives as CCK receptor antagonists
• Brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors
• Antispasmodic agents
• β-carbolinium cations as new antimalarial agents

Packaging

5, 25 g in poly bottle

Biochem/physiol Actions

Vasoactive; may have a neuromodulator function.

Other Notes

Biogenic amine formed from the decarboxylation of tryptophan by L-aromatic amino acid decarboxylase.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NL4375000

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

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