EMAIL THIS PAGE TO A FRIEND
253359 Sigma-Aldrich

4-Maleimido-TEMPO

for ESR-spectroscopy

Synonym: 4-Maleimido-2,2,6,6-tetramethyl-1-piperidinyloxy, free radical

  • CAS Number 15178-63-9

  • Empirical Formula (Hill Notation) C13H19N2O3

  • Molecular Weight 251.30

  •  MDL number MFCD00010110

  •  PubChem Substance ID 24855307

Purchase

Properties

Related Categories Chemical Synthesis, Radical Chemistry, Stable Radicals, Synthetic Reagents, TEMPO Derivatives More...
grade   for ESR-spectroscopy
description   free radical
InChI Key   CMNDHIFMYRPBGH-UHFFFAOYSA-N
mp   91-94 °C (lit.)
storage temp.   2-8°C

Description

General description

4-Maleimido-TEMPO, a water-soluble nitroxide radical, is commonly employed as spin probe. It has been reported to inhibit the survival of CHO cells at 1mM concentrations. It is widely employed maleimide spin label for EPR studies.

Application

4-Maleimido-TEMPO (4-Maleimido-2,2,6,6,-tetramethylpiperidinooxyl) was employed as spin label to investigate the influence of bile salts on the intact rat mitochondrial membranes by electron paramagnetic resonance spectroscopy (EPR). It may be employed as spin label for the labeling of erythrocyte membranes to investigate the interaction of quercetin with erythrocyte proteins by EPR spectra.

Packaging

10, 25 mg in clear glass bottle

Biochem/physiol Actions

Spin label used to study fluidity of brain synaptosomal membranes, internal microviscosity of erythrocytes, and human high density lipoproteins.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles

Articles

TEMPO Catalyzed Oxidations

TEMPO (2,2,6,6-Tetramethylpiperidinyloxy or 2,2,6,6-Tetramethylpiperidine 1-oxyl) and its derivatives are stable nitroxy radicals used as catalysts in organic oxidation reactions. TEMPO was discovere...
Keywords: Aerobic, Capillary electrophoresis, Catalysis, Chromatography, Coupling reactions, Oxidations, Polymerization reactions, Size-exclusion chromatography, Solvents

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?