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257370 Sigma-Aldrich

7-Amino-4-methylcoumarin

99%

Synonym: Coumarin 120

  • CAS Number 26093-31-2

  • Empirical Formula (Hill Notation) C10H9NO2

  • Molecular Weight 175.18

  •  Beilstein/REAXYS Number 142231

  •  EC Number 247-454-8

  •  MDL number MFCD00006868

  •  PubChem Substance ID 57648146

  •  NACRES NA.23

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Properties

Related Categories Biochemicals and Reagents, Derivatization agents, Fluorescent Labels, Fluorescent Probes, Labels, Particles and Stains, Laser Dyes,
Quality Level   200
description   chromophore for enzyme substrates
assay   99%
mp   223-226 °C (lit.)
λmax   354 nm in ethanol
storage temp.   2-8°C
SMILES string   CC1=CC(=O)Oc2cc(N)ccc12
InChI   1S/C10H9NO2/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3
InChI key   GLNDAGDHSLMOKX-UHFFFAOYSA-N

Description

General description

7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.

Application

Coumarin 120 is used as a fluorescent labeling reagent for trace determination of enzymes. It may be used as an antibacterial agent against MDR isolates of M. tuberculosis as it impacts the cell morphology. Coumarin 120 may also be used as an electron donor (amino groups) to transfer charge in a fluorescent sensor for the detection of mercury ions in aqueous media.

Packaging

100, 500 mg in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Fluorescence Quenching Microscopy: Imaging Two-Dimensional Materials

Alane Lim and Jiaxing Huang* Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA *Email: jiaxing-huang@northwestern.edu
Keywords: Chemical vapor deposition, Deposition, Diffraction, Materials Science, Microscopy, Optical microscopy, Scanning electron microscopy, Solvents, Spectroscopy, Spin coating

Graphene in Biotechnology

Alba Centeno and Amaia Zurutuza Elorza* Graphenea S.A. Tolosa Hiribidea, 76, E-20018 Donostia - San Sebastian, Spain *Email: a.zurutuza@graphenea.com
Keywords: Adsorption, Angiogenesis, Bacterial conjugations, Building blocks, Cancer, Chemical vapor deposition, Degradations, Deposition, Diffusion, Diseases, Electronics, Gene expression, Growth factors, Immunostaining, Infrared spectroscopy, Ligands, Magnetic resonance imaging, Microscopy, Nanoelectronics, Nanomaterials, Nanotubes, Neuroscience, Nucleic acid hybridization, Positron Emission Tomography, Scanning electron microscopy, Transfection, Transmission electron microscopy

Peer-Reviewed Papers
15

References

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