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263478 Sigma-Aldrich

4-Bromo-1,2-difluorobenzene

98%

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Properties

Related Categories Aryl, Aryl Fluorinated Building Blocks, Building Blocks, C6, Chemical Synthesis,
InChI Key   YMQPKONILWWJQG-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.505(lit.)
bp   150-151 °C(lit.)
density   1.707 g/mL at 25 °C(lit.)

Description

Packaging

10 g in ampule

Application

4-Bromo-1,2-difluorobenzene has been used in the preparation of 4-benzyl-2-(3,4-difluorophenyl)-2-hydroxy-morpholine.

General description

Regioselective nucleophilic aromatic substitution reaction of 4-bromo-1,2-difluorobenzene with benzyl alcohol has been investigated.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 1993C 3 / PGIII
WGK Germany 
2
Flash Point(F) 
91.4 °F
Flash Point(C) 
33 °C

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Protocols & Articles
Peer-Reviewed Papers
15

References

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Z693847 Scienceware® Break-Safe ampule opener

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43917 SnapIT Ampule Opener, large, for 5-10ml, 10-15ml, 20-25ml ampoules

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