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271594 Sigma-Aldrich

5-Fluorocytosine

99%

Synonym: 4-amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine

  • CAS Number 2022-85-7

  • Empirical Formula (Hill Notation) C4H4FN3O

  • Molecular Weight 129.09

  •  Beilstein/REAXYS Number 127285

  •  EC Number 217-968-7

  •  MDL number MFCD00006035

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Properties

InChI Key   XRECTZIEBJDKEO-UHFFFAOYSA-N
assay   99%
mp   298-300 °C (dec.) (lit.)

Description

Biochem/physiol Actions

Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
HA6040000
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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F7129 5-Fluorocytosine, nucleoside analog

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