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284262 Sigma-Aldrich

Iodoacetic anhydride

  • CAS Number 54907-61-8

  • Linear Formula (ICH2CO)2O

  • Molecular Weight 353.88

  •  Beilstein/REAXYS Number 1812140

  •  MDL number MFCD00001080

  •  PubChem Substance ID 24857144

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Carboxylic Acid Anhydrides, Chemical Synthesis, Organic Building Blocks More...
Quality Level   100
mp   47-49 °C (lit.)
solubility   chloroform: soluble 10%, clear to slightly hazy, yellow (pink or tan)
storage temp.   2-8°C
SMILES string   ICC(=O)OC(=O)CI
InChI   1S/C4H4I2O3/c5-1-3(7)9-4(8)2-6/h1-2H2
InChI key   RBNSZWOCWHGHMR-UHFFFAOYSA-N

Description

Application

Reagent used as linker for development of reagents used for differential protein quantitation via ion scanning

Reactant used for:
• Sythesis of N-iodoacetyl glycosylamine derivatives and converting amino precursors to IA derivatives
• Linking lysine residues to N-terminal α-amino groups of peptides
• Capping amines and yielding a thiol reactive iodo-derivative
• Iodoacetylation

Packaging

1 g in glass bottle

250 mg in amber glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
230.0 °F - closed cup
Flash Point(C) 
110 °C - closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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