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300977 Sigma-Aldrich

(R)-4-Benzyl-2-oxazolidinone

99%

  • CAS Number 102029-44-7

  • Empirical Formula (Hill Notation) C10H11NO2

  • Molecular Weight 177.20

  •  Beilstein/REAXYS Number 4782551

  •  MDL number MFCD00010846

  •  PubChem Substance ID 24858151

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Auxiliaries, Oxazolidinone Derivatives
InChI Key   OJOFMLDBXPDXLQ-SECBINFHSA-N
assay   99%
optical activity   [α]18/D +64°, c = 1 in chloroform
mp   88-90 °C

Description

Application

(R)-4-Benzyl-2-oxazolidinone may be used as a starting material in the synthesis of enantiopure carbocyclic nucleosides. It may also be used as a chiral auxiliary in the enantioselective synthesis of (2R,2′S)-erythro-methylphenidate.

Used in the synthesis of HIV protease inhibitors.

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta.

Packaging

1, 5, 25 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

HPLC Analysis of 4-Benzyl-2-oxazolidinone Enantiomers on Astec® CHIROBIOTIC® TAG

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of 4-Benzyl-2-oxazolidinone Enantiomers on Astec® CHIROBIOTIC® TAG
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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