• USA Home
  • 341347 - Bis(diisopropylamino)chlorophosphine

EMAIL THIS PAGE TO A FRIEND
341347 Sigma-Aldrich

Bis(diisopropylamino)chlorophosphine

≥95.0%

Synonym: Chlorobis(N,N-diisopropyl)phosphoramidite, Chlorobis(N,N-diisopropylamino)phosphine, Tetraisopropylphosphorodiamidous chloride

  • CAS Number 56183-63-2

  • Linear Formula [[(CH3)2CH]2N]2PCl

  • Molecular Weight 266.79

  •  MDL number MFCD00061482

  •  PubChem Substance ID 24860930

  •  NACRES NA.22

Purchase

Properties

Related Categories Catalysis and Inorganic Chemistry, Chemical Synthesis, Phosphine Compounds, Phosphorus Precursors
Quality Level   100
assay   ≥95.0%
reaction suitability   reaction type: Buchwald-Hartwig Cross Coupling Reaction
  reaction type: Heck Reaction
  reaction type: Hiyama Coupling
  reaction type: Negishi Coupling
  reaction type: Sonogashira Coupling
  reaction type: Stille Coupling
  reaction type: Suzuki-Miyaura Coupling
  reagent type: ligand
mp   100-104 °C (lit.)
functional group   phosphine
SMILES string   CC(C)N(C(C)C)P(Cl)N(C(C)C)C(C)C
InChI   1S/C12H28ClN2P/c1-9(2)14(10(3)4)16(13)15(11(5)6)12(7)8/h9-12H,1-8H3
InChI key   FEHUTHGOLLQBNW-UHFFFAOYSA-N

Description

Application

Bis(diisopropylamino)chlorophosphine has been used in the synthesis of tert-butyl tetraisopropylphosphorodiamidite ligand for palladium-catalyzed Buchwald–Hartwig amination reaction.

It is also can be used to synthesize:
• acyclic N-phosphonio imine catalyst for selective epoxidations
• boryl-substituted methylenephosphonium derivatives

Packaging

5 g in glass bottle

Other Notes

Contains varying amounts of diisopropylamine hydrochloride

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
EUH014
RIDADR 
UN 3261 8 / PGI
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Catalysts
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?