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342300 Sigma-Aldrich

2-Amino-6-chloropurine

97%

Synonym: 6-Chloro-2-purinamine, 6-Chloroguanine

  • CAS Number 10310-21-1

  • Empirical Formula (Hill Notation) C5H4ClN5

  • Molecular Weight 169.57

  •  Beilstein/REAXYS Number 9626

  •  EC Number 233-686-7

  •  MDL number MFCD00075252

  •  PubChem Substance ID 24861051

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Properties

Related Categories Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Purines More...
InChI Key   RYYIULNRIVUMTQ-UHFFFAOYSA-N
assay   97%
mp   >300 °C (lit.)

Description

General description

2-Amino-6-chloropurine is a 6-substituted purine. Tautomeric purine forms of 2-amino-6-chloropurine were investigated by vibrational spectroscopy and quantum chemical method.

Application

2-Amino-6-chloropurine may be used:
• in the enzymatic synthesis of 2′-deoxyguanosine
• in the synthesis of 9-alkyl purines
• in the synthesis of (R)- and (S)-N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases

Packaging

1, 5 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UO7502000

Documents

Certificate of Analysis

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Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

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