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347795 Sigma-Aldrich

Sodium dichloroacetate


Synonym: Dichloroacetic acid sodium salt



Related Categories Aerobic Glycolysis (the Warburg Effect), Cancer Metabolism, Cancer Research, Cell Biology, Chemical Synthesis,
Quality Level   100
assay   98%
impurities   <2% ethyl alcohol
mp   198 °C (dec.) (lit.)
SMILES string   [Na+].[O-]C(=O)C(Cl)Cl
InChI   1S/C2H2Cl2O2.Na/c3-1(4)2(5)6;/h1H,(H,5,6);/q;+1/p-1
Gene Information   human ... PDK1(5163), PDK2(5164), PDK3(5165), PDK4(5166)


General description

Sodium dichloroacetate is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor that exhibits potent anti-leukemic activity.


Sodium dichloroacetate can be used as an organic salt precursor for synthesizing microporous carbon that is useful in developing carbon-based adsorbents.


10, 50 g in glass bottle

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Target organs 
Respiratory system
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
I have heard that dichloroacetate has been used for cancer treatment.IsProduct 347795, Sodium dichloroacetate, the same chemical?
Some research studies on the use of dichloroacetate as an anti-cancer agent have been performed.At this time, no dichloroacetate compound or product has been approved for use as an anti-cancer drug.The common salts of dichloroacetate are sodium and potassium, and these are what have been used in the research studies.The Sigma-Aldrich products 347795, Sodium Dichloroacetate, and 348082, Potassium Dichloroacetate, are offered for laboratory use only, and are not manufactured or intended for human use.
How can I make a solution of Product 347795, Sodium dichloroacetate?
Sodium dichloroacetate is soluble in water at 50 mg/ml.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Protocols & Articles


Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
BioFiles v7 n4
Keywords: Aerobic, Cancer, Cell proliferation, Clinical, Glycolysis, Phosphorylations, Transcription

Peer-Reviewed Papers


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