• USA Home
  • 349852 - [3-(Ethoxycarbonyl)propyl]triphenylphosphonium bromide

EMAIL THIS PAGE TO A FRIEND
349852 Sigma-Aldrich

[3-(Ethoxycarbonyl)propyl]triphenylphosphonium bromide

97%

Synonym: NSC 269919

  • CAS Number 50479-11-3

  • Linear Formula C2H5O2C(CH2)3P(C6H5)3Br

  • Molecular Weight 457.34

  •  MDL number MFCD00274610

  •  PubChem Substance ID 24861713

  •  NACRES NA.22

Purchase

Properties

Related Categories C-C Bond Formation, Chemical Synthesis, Olefination, Synthetic Reagents, Wittig Reagents More...
assay   97%
reaction suitability   reaction type: C-C Bond Formation
mp   165-167 °C (lit.)
storage temp.   room temp
SMILES string   [Br-].CCOC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
InChI   1S/C24H26O2P.BrH/c1-2-26-24(25)19-12-20-27(21-13-6-3-7-14-21,22-15-8-4-9-16-22)23-17-10-5-11-18-23;/h3-11,13-18H,2,12,19-20H2,1H3;1H/q+1;/p-1
InChI key   JPZMNVPVVYVXAD-UHFFFAOYSA-M

Description

Application

Reactant for:
• Asymmetric synthesis of antihypercholesterolemic ezetimibe via Wittig reaction
• Wittig reactions

[3-(Ethoxycarbonyl)propyl]triphenylphosphonium bromide can be used:
• As a reactant in the synthesis of spirocyclic GPR119 agonists.
• In the synthesis of cyclic acetal intermediate of azadirachtin, a terpenoid found in the neem tree Azadirachta indica.
• To prepare a catechin metabolite named 5-(3,4,5-trihydroxyphenyl)valeric acid.

Packaging

25 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?