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360139 Sigma-Aldrich

5′-O-(4,4′-Dimethoxytrityl)thymidine

98%

Synonym: DMT-T

  • CAS Number 40615-39-2

  • Empirical Formula (Hill Notation) C31H32N2O7

  • Molecular Weight 544.59

  •  Beilstein/REAXYS Number 599297

  •  EC Number 255-003-1

  •  MDL number MFCD00010113

  •  PubChem Substance ID 24862149

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, C12 to C30+, Chemical Synthesis, Heterocyclic Building Blocks, Pyrimidines More...
Quality Level   100
assay   98%
mp   114-116 °C (subl.) (lit.)
storage temp.   2-8°C
SMILES string   COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2O)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5
InChI   1S/C31H32N2O7/c1-20-18-33(30(36)32-29(20)35)28-17-26(34)27(40-28)19-39-31(21-7-5-4-6-8-21,22-9-13-24(37-2)14-10-22)23-11-15-25(38-3)16-12-23/h4-16,18,26-28,34H,17,19H2,1-3H3,(H,32,35,36)/t26-,27+,28+/m0/s1
InChI key   UBTJZUKVKGZHAD-UPRLRBBYSA-N

Description

General description

5′-O-(4,4′-Dimethoxytrityl)thymidine is a pyrimidine.

Application

5′-O-(4,4′-Dimethoxytrityl)thymidine may be used in the stereoselective synthesis of 3′-deoxy-3′-threo-hydroxymethyl nucleoside, which can be subsequently incorporated into oligodeoxynucleotides. It may be used as research tool for antiviral and anticancer studies.

Packaging

1 g in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

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Protocols & Articles
Peer-Reviewed Papers
15

References

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