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361399 Sigma-Aldrich

Tetrabutylammonium fluoride solution

75 wt. % in H2O

Synonym: TBAF solution

  • CAS Number 429-41-4

  • Linear Formula [CH3(CH2)3]4NF

  • Molecular Weight 261.46

  •  Beilstein/REAXYS Number 3762762

  •  MDL number MFCD00011747

  •  PubChem Substance ID 24862218

  •  NACRES NA.22

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Properties

Related Categories Chemical Synthesis, Deprotecting Reagents, Fluoride Sources, Protection and Derivatization, Synthetic Reagents More...
concentration   75 wt. % in H2O
density   0.953 g/mL at 25 °C
storage temp.   room temp
SMILES string   [F-].CCCC[N+](CCCC)(CCCC)CCCC
InChI   1S/C16H36N.FH/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1
InChI key   FPGGTKZVZWFYPV-UHFFFAOYSA-M

Description

Application

Reactant for preparation of:
• Triple monoamine reuptake inhibitors as a new generation of antidepressants
• Alcohols via hydrolysis of alkyl silyl ethers neutral pH in mixed organic-aqueous buffered solutions
• Oligoribonucleotides with phosphonate-modified linkages
• Aryl alkyl alcohols via Nozaki-Hiyama allylation catalyzed by chiral bipyridyldiol ligands and chromium trichloride
• Conjugated dienoic acid esters using Suzuki coupling reactions
• Macrocyclic o-aminobenzamide Hsp90 inhibitorwith antitumor activity
• Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors
• Anti-diabetic polyacetylenic glucosides

Packaging

100, 500 g in poly bottle

25 g in amber poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1760 8 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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