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365564 Sigma-Aldrich

Methyl 4-methoxy-2-indolecarboxylate

99%

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Properties

Related Categories Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   GLCZQTLCVLVFGV-UHFFFAOYSA-N
assay   99%
mp   140-142 °C (lit.)

Description

General description

Methyl 4-methoxy-2-indolecarboxylate is an indole derivative.

Application

• reactant in [3+2] annulation reactions
• reactant in preparation of inhibitors of mammalian secreted phospholipases A2
• reactant in Heck reactions
• reactant in preparation of indole fatty alcohol derivatives
• reactant in methylation reactions

Methyl 4-methoxy-2-indolecarboxylate is suitable for use in the production of dyes by Escherichia coli expressing naphthalene dioxygenase (NDO) and toluene dioxygenase (TDO). It is also suitable for use in the production of dyes by E. coli expressing multicomponent phenol hydroxylase (mPH) from Pseudomonas sp. strains KL33 and KL28.

Packaging

1 g in glass bottle

250 mg in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Building blocks, Cardiovascular, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Peer-Reviewed Papers
15

References

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