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365645 Sigma-Aldrich

Andrographolide

98%

  • CAS Number 5508-58-7

  • Empirical Formula (Hill Notation) C20H30O5

  • Molecular Weight 350.45

  •  Beilstein Registry Number 42762

  •  EC Number 226-852-5

  •  MDL number MFCD07778082

  •  PubChem Substance ID 24862550

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Complex Molecules
InChI Key   BOJKULTULYSRAS-OTESTREVSA-N
assay   98%
optical activity   [α]20/D −126°, c = 1.5 in acetic acid
mp   229-232 °C (lit.)

Description

Biochem/physiol Actions

Diterpenoid lactone with anti-inflammatory properties. It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement. Blocks the proliferation of several cancer cell lines in vitro.

Packaging

100 mg in clear glass bottle

500 mg in amber glass bottle

General description

Andrographolide, a bioactive diterpene lactone, is the main constituent of Andrographis paniculata, a plant used in traditional medicines. It is known to have different biological activities such as anti-inflammatory, anti-malarial, anti-cancer and hepatoprotective activity. It also shows potent anti-viral effect against dengue virus.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
LU3490750

Documents

Certificate of Analysis

Certificate of Origin


Same Products - New Packaging
Protocols & Articles
Peer-Reviewed Papers
15

References

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