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382256 Sigma-Aldrich

4-Hydroxy-8-(trifluoromethyl)quinoline

98%

Synonym: 8-(Trifluoromethyl)-4-quinolinol

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Properties

Related Categories Building Blocks, C8 to C10, Chemical Synthesis, Heterocyclic Building Blocks, Quinolines More...
assay   98%
mp   174-176 °C (lit.)
SMILES string   Oc1ccnc2c(cccc12)C(F)(F)F
InChI   1S/C10H6F3NO/c11-10(12,13)7-3-1-2-6-8(15)4-5-14-9(6)7/h1-5H,(H,14,15)
InChI key   UDRWADJLLWWJOE-UHFFFAOYSA-N

Description

General description

4-Hydroxy-8-(trifluoromethyl)quinolone (8-(Trifluoromethyl)-4-quinolinol) is a heterocyclic building block. Various 4-hydroxy-8-trifluoromethyl-quinoline derivatives have been prepared via multi step reactions and were tested for their antimicrobial actions.

Application

4-Hydroxy-8-(trifluoromethyl)quinolone (4-Hydroxy-8-trifluoromethylquinolone) may be used in the synthesis of analgesic compound, floctafenine.

Packaging

1 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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