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384321 Sigma-Aldrich

Propargyl chloride solution

70 wt. % in toluene

Synonym: 3-Chloro-1-propyne

  • CAS Number 624-65-7

  • Linear Formula HC≡CCH2Cl

  • Molecular Weight 74.51

  •  Beilstein Registry Number 506005

  •  MDL number MFCD00000980

  •  PubChem Substance ID 24863662

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Properties

Related Categories Alkynes, Building Blocks, Chemical Synthesis, Organic Building Blocks, Terminal More...
InChI Key   LJZPPWWHKPGCHS-UHFFFAOYSA-N
concentration   70 wt. % in toluene
refractive index   n20/D 1.456
density   0.963 g/mL at 25 °C
storage temp.   2-8°C

Description

Packaging

100 mL in glass bottle

Application

Propargyl chloride may be used as propargylating agent in the preparation of arabinogalactan propargyl ethers with degree of substitution up to 1.8. It may be used for the in situ preparation of propargyltrichlorosilane and allenyltrichlorosilane, required for the synthesis of optically active allenic and homopropargylic alcohols.

Propargyl chloride solution may be used for the enantioselective synthesis of enantiomerically enriched homopropargyl alcohols.

General description

Product is the 70wt.% solution of propargyl chloride in toluene. Propargyl chloride is a propargyl halide. Its trimethylsilylation reaction has been reported. Liquid-phase Raman spectra, and vapor-phase and solution-phase infrared spectra of propargyl chloride has been studied at 100-3400cm-1 and 300-3800cm-1, respectively. It participates in the addition reaction with acyclic 1,3-dienes (at -78°C) in the presence of zinc chloride.

Safety & Documentation

Safety Information

Signal word 
Danger
RIDADR 
UN 3286 8(6.1)(3) / PGII
WGK Germany 
3
Flash Point(F) 
66.2 °F
Flash Point(C) 
19 °C

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Peer-Reviewed Papers
15

References

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