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384321 Sigma-Aldrich

Propargyl chloride solution

70 wt. % in toluene

Synonym: 3-Chloro-1-propyne

  • CAS Number 624-65-7

  • Linear Formula HC≡CCH2Cl

  • Molecular Weight 74.51

  •  Beilstein/REAXYS Number 506005

  •  MDL number MFCD00000980

  •  PubChem Substance ID 24863662

  •  NACRES NA.22

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Properties

Related Categories Alkynes, Building Blocks, Chemical Synthesis, Organic Building Blocks, Terminal More...
Quality Level   100
concentration   70 wt. % in toluene
refractive index   n20/D 1.456
density   0.963 g/mL at 25 °C
storage temp.   2-8°C
SMILES string   ClCC#C
InChI   1S/C3H3Cl/c1-2-3-4/h1H,3H2
InChI key   LJZPPWWHKPGCHS-UHFFFAOYSA-N

Description

General description

Product is the 70wt.% solution of propargyl chloride in toluene. Propargyl chloride is a propargyl halide. Its trimethylsilylation reaction has been reported. Liquid-phase Raman spectra, and vapor-phase and solution-phase infrared spectra of propargyl chloride has been studied at 100-3400cm-1 and 300-3800cm-1, respectively. It participates in the addition reaction with acyclic 1,3-dienes (at -78°C) in the presence of zinc chloride.

Application

Propargyl chloride may be used as propargylating agent in the preparation of arabinogalactan propargyl ethers with degree of substitution up to 1.8. It may be used for the in situ preparation of propargyltrichlorosilane and allenyltrichlorosilane, required for the synthesis of optically active allenic and homopropargylic alcohols.

Propargyl chloride solution may be used for the enantioselective synthesis of enantiomerically enriched homopropargyl alcohols.

Packaging

100 mL in glass bottle

Safety & Documentation

Safety Information

Signal word 
Danger
Target organs 
Central nervous system
RIDADR 
UN 3286 8(6.1)(3) / PGII
WGK Germany 
WGK 2
Flash Point(F) 
66.2 °F
Flash Point(C) 
19 °C

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Peer-Reviewed Papers
15

References

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