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391956 Sigma-Aldrich

Dimethylamine solution

2.0 M in THF

  • CAS Number 124-40-3

  • Linear Formula (CH3)2NH

  • Molecular Weight 45.08

  •  Beilstein/REAXYS Number 605257

  •  MDL number MFCD00008288

  •  PubChem Substance ID 24864412

  •  NACRES NA.22

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Properties

Related Categories Acids & Bases, Arbidol, Bases, Camostat Mesylate, Chemical Synthesis,
Quality Level   200
assay   1.90-2.20 M (by NaOH, titration)
form   liquid
concentration   2.0 M in THF
bp   ~60 °C
density   0.85 g/mL at 25 °C
SMILES string   CNC
InChI   1S/C2H7N/c1-3-2/h3H,1-2H3
InChI key   ROSDSFDQCJNGOL-UHFFFAOYSA-N

Description

Application

Dimethylamine solution (2M in THF) has been used in the synthesis of 2-dimethylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (bk-MDDMA) , a β-keto derivative of 3,4-methylenedioxyamphetamine (MDA) by reacting with 2-bromo-3′,4′-methylenedioxypropiophenone. It may also be used to synthesize organic intermediates such as dimethyl-(4-nitro-benzyl)-amine, dimethyl-(4-methyl-benzyl)-amine and 4-dimethylamino-but-2-enoic acid [4-(3,4-dichloro-6-fluoro-phenylamino)-quinazolin-6-yl]-amide.

Packaging

100, 800 mL in Sure/Seal™

Safety & Documentation

Safety Information

Signal word 
Danger
Target organs 
Respiratory system
Supplemental Hazard Statements 
EUH019
RIDADR 
UN 2924 8(3) / PGII
WGK Germany 
WGK 2
Flash Point(F) 
-32.8 °F - closed cup
Flash Point(C) 
-36 °C - closed cup

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

GC Analysis of Amines in Water on SPB®-1 SULFUR after SPME using 65 μm PDMS/DVB Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Amines in Water on SPB®-1 SULFUR after SPME using 65 μm PDMS/DVB Fiber
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Residual Solvents on SPB®-1 SULFUR after SPME using 65 μm PDMS/DVB Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Residual Solvents on SPB®-1 SULFUR after SPME using 65 μm PDMS/DVB Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Purification, Solid phase microextractions

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Peer-Reviewed Papers
15

References

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