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393711 Sigma-Aldrich

2′,3′-Dideoxy-3′-fluorouridine

95%

Synonym: 3′-Fluoro-2′,3′-dideoxyuridine

  • CAS Number 41107-56-6

  • Empirical Formula (Hill Notation) C9H11FN2O4

  • Molecular Weight 230.19

  •  Beilstein/REAXYS Number 6064366

  •  EC Number 415-360-8

  •  MDL number MFCD00192015

  •  PubChem Substance ID 24864537

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, C9 to C11, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks,
Quality Level   100
assay   95%
optical activity   [α]20/D +10.5°, c = 0.5 in 1 M NaOH
mp   184-188 °C (lit.)
SMILES string   OC[C@H]1O[C@H](C[C@@H]1F)N2C=CC(=O)NC2=O
InChI   1S/C9H11FN2O4/c10-5-3-8(16-6(5)4-13)12-2-1-7(14)11-9(12)15/h1-2,5-6,8,13H,3-4H2,(H,11,14,15)/t5-,6+,8+/m0/s1
InChI key   BKIUEHLYJFLWPK-SHYZEUOFSA-N

Description

General description

2′,3′-Dideoxy-3′-fluorouridine (3’-fluoro-2’,3’-dideoxyuridine, FddUrd) is a fluorinated pyrimidine nucleoside analog of uridine. It has been studied extensively for its potential use as an antiviral agent against HIV.

Application

2′,3′-Dideoxy-3′-fluorouridine can be used as a starting material in the synthesis of:
•  3-fluoro 2,3-dideoxynucleoside analogs for in vitro antiviral activity studies.
•  3-fluoro deoxyuridine monophosphate analogs as potential anti parasites.

Packaging

25, 100 mg in clear glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

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Protocols & Articles
Peer-Reviewed Papers
15

References

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