• USA Home
  • 407135 - (1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol

EMAIL THIS PAGE TO A FRIEND
407135 Sigma-Aldrich

(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol

97%

Synonym: (+)-DBNE, N,N-Dibutyl-L-(+)-norephedrine

Purchase

Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Auxiliaries, Ephedrine Derivatives
InChI Key   BRRGNOFUBFINSX-RDJZCZTQSA-N
assay   97%
optical activity   [α]20/D +21°, c = 2 in chloroform
refractive index   n20/D 1.501 (lit.)
bp   121 °C/0.1 mmHg(lit.)
density   0.94 g/mL at 25 °C (lit.)

Description

General description

(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol, a norephedrine derivative, is a chiral auxiliary for asymmetric synthesis.

Application

(+)-DBNE reacts with nickel bromide (NiBr2) to form a chiral catalyst, which can catalyze the enantioselective conjugate addition of dialkylzincs to α,β-unsaturated ketones leading to the formation of optically active β-substituted ketones.

Packaging

1 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
230 °F
Flash Point(C) 
110 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?