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  • 408727 - Polyethylenimine, branched

408727 Sigma-Aldrich

Polyethylenimine, branched

average Mw ~25,000 by LS, average Mn ~10,000 by GPC, branched

Synonym: PEI



Related Categories Branched PEI, Hydrophilic Polymers, Materials Science, Poly(2-oxazoline) and Polyethylenimine (PEI), Polyethylenimine (PEI),
Quality Level   200
mol wt   average Mn ~10,000 by GPC
  average Mw ~25,000 by LS
impurities   ≤1% water
refractive index   n20/D 1.5290
viscosity   13,000-18,000(50 °C)
bp   250 °C (lit.)
density   1.030 g/mL at 25 °C
SMILES string   C1CN1
InChI   1S/C2H5N/c1-2-3-1/h3H,1-2H2



Used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
Detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.


1 L in poly bottle

100, 250 mL in poly bottle

Physical form

Branched polymer

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
UN 3082 9 / PGIII
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the concentration and purity of Polyethylenimine, Product 408727?
This product is the pure product of polyethyleneimine. At room temperature this product is a liquid and not a solid. The purity of this product is not routinely determined.
At what temperature does Product 408727, Polyethylenimine, decompose?
Polyethylenimine (mw ~25,000) begins to decompose at 225 °C.
What is the solubility of Product 408727, Polyethylenimine?
We do not test the solubility of this product.However, according to our supplier, this product is miscible with water and ethylene glycol, and soluble in ethanol.
What are the end groups on Product 408727, Polyethylenimine?
The end groups are primary, secondary, and tertiary amines that are in a ratio of 1 : 1.2 : 0.76, respectively.
What is the water content of Product 408727, Polyethylenimine?
This product will contain less than 1% water. The lot specific value is reported on the Certificate of Analysis.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Protocols & Articles


Functionalized Pei and Its Role in Gene Therapy

1Department of Pharmacy, Pharmaceutical Technology and Biopharmacy,  Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377  München, Germany 2Nanosystems Initiative Munich (NIM), Ludwig-Ma...
Bettina Schwarz,1 Olivia M. Merkel1,2*
Material Matters, 2017, 12.2
Keywords: Bacterial conjugations, Clinical, Condensations, Degradations, Diseases, Gene expression, Genetic, Infrared spectroscopy, Ligands, Michael Addition, Microscopy, Nanotubes, Pharmaceutical, Reductions, Substitutions, Transfection

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Department of Chemistry and Biochemistry, Faculty of Engineering, Kyushu University, Japan *E-mail: ykatatcm@mail.cstm.kyushu-u.ac.jp
Keywords: Amplification, Angiogenesis, Biochemistry, Cancer, Cardiovascular, Clinical, Diagnostic, Electron spin resonance, Enzyme activity, Gene expression, Genetic, Infrared spectroscopy, Reductions, Transcription

Novel Inks for Direct-Write Assembly of 3-D Periodic Structures

New methods for materials fabrication at the micro- and nanoscale will drive scientific and technological advances in areas of materials science, chemistry, physics, and biology. The broad diversity ...
Prof. Jennifer A. Lewis
Material Matters 2008, 3.1, 4.
Keywords: Applications, Biomaterials, Capabilities, Coagulants, Coagulation, Deposition, Environmental, Materials Science, Methods, Photographs, Reductions, Semiconductor, Size-exclusion chromatography, Sol-gel, Support, Type

Polyelectrolyte Multilayer Films and Membrane Functionalization

Among the many methods for preparing thin films, layer-by-layer (LbL) deposition of complementary polymers has emerged as an especially versatile technique for controlling film thickness and function...
Merlin L. Bruening, Maneesha Adusumilli
Material Matters Volume 6 Number 3
Keywords: Adsorption, Catalysis, Deposition, Diffusion, Digestions, Electrophoresis, Gel electrophoresis, Immobilization, Mass spectrometry, Nanotechnology, Phase transitions, Reductions

Recent Progress on Nonviral Delivery Carriers for CRISPR/Cas9 Systems

State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Functional Polymer Materials of Ministry of Education, College of Chemistry, Nankai University, National Demonstration Center for...
Keywords: Adsorption, Chemical biology, Clinical, Combinatorial library, Condensations, Degradations, Gene expression, Gene knockdown, Ligands, Metal organic frameworks, Transfection

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