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415057 Sigma-Aldrich

Magnesium stearate

technical grade

Synonym: Stearic acid magnesium salt

  • CAS Number 557-04-0

  • Linear Formula [CH3(CH2)16CO2]2Mg

  • Molecular Weight 591.24

  •  Beilstein/REAXYS Number 3919702

  •  EC Number 209-150-3

  •  MDL number MFCD00036391

  •  PubChem Substance ID 24865972

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Carboxylic Acid Salts, Chemical Synthesis, Organic Building Blocks More...
Quality Level   100
grade   technical grade
composition   palmitate salt, 25%
  stearate salt, 65%
mp   200 °C (lit.)
SMILES string   CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
InChI   1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChI key   HQKMJHAJHXVSDF-UHFFFAOYSA-L

Description

General description

Magnesium stearate (Mg-St) is the magnesium salt of stearic acid. Its anhydrate, dihydrate and trihydrate forms have been prepared. The tabletting of the blends of magnesium stearate and lactose granules has been described. The influence of mixing time on hardness, disintegration time and ejection force on the compressed tablets was examined. Mg-St is widely used lubricant in pharmaceutical industry. It also plays a role in delaying the process of dissolution. Its detection in tablets by laser-induced breakdown spectroscopy has been proposed.

Application

Magnesium stearate may be used as excipient in the formulations of diclofenac sodium tablets. It may be used for the preparation of tramadol HCl matrix tablets.

Packaging

1 kg in poly drum

25 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
RTECS 
WI4390000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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