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415324 Sigma-Aldrich

N-Isopropylacrylamide

97%

Synonym: NIPAM

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Properties

Related Categories Acrylamide and Methacrylamide, Acrylic Monomers, Materials Science, Monomers, Polymer Science More...
Quality Level   100
assay   97%
bp   89-92 °C/2 mmHg (lit.)
mp   60-63 °C (lit.)
SMILES string   CC(C)NC(=O)C=C
InChI   1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChI key   QNILTEGFHQSKFF-UHFFFAOYSA-N

Description

General description

N-Isopropylacrylamide (NIPAM) is a biocompatible monomeric unit that can be used in the formation of stimuli responsive polymers due to its temperature sensitive properties, which include temperature based volumetric and phase changes. These properties change when the temperature of the solution reaches a lower critical solution temperature (LCST).

Application

NIPAM can be used to prepare poly(NIPAM) that can be used for a variety of applications such as tissue engineering, cell culture, biomedical coating, drug delivery, and muscle regeneration.

Packaging

10, 50 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
AS3675000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.1 Nonetheless, major challenges still need ...
Masamichi NakayamaTeruo Okano and Françoise M. Winnik
Material Matters 2010, 5.3, 56.
Keywords: Adhesion, Biomaterials, Cell culture, Clinical, Dehydration reaction, Growth factors, Hydration reaction, Immobilization, Inflammation, Ligands, Magnetic resonance spectroscopy, Polymerization reactions, Radical polymerization, Rearrangements, Reversible addition-fragmentation chain transfer polymerizations, Solvents

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Explore our portfolio of well characterized, competitively priced products for your materials synthesis needs. This includes salts, deposition precursors, metals, alloys, ceramics and monomers, polym...
Keywords: Ceramics, Deposition, Materials Science

Peer-Reviewed Papers
15

References

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