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419362 Sigma-Aldrich

Di-tert-butyl N,N-diisopropylphosphoramidite

95%

  • CAS Number 137348-86-8

  • Linear Formula [(CH3)2CH]2NP[OC(CH3)3]2

  • Molecular Weight 277.38

  •  Beilstein Registry Number 4858847

  •  MDL number MFCD00153506

  •  PubChem Substance ID 24866105

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Properties

Related Categories Catalysis and Inorganic Chemistry, Chemical Biology, Chemical Synthesis, Coupling Reagents, Nucleoside Chemistry,
InChI Key   YGFLCNPXEPDANQ-UHFFFAOYSA-N
assay   95%
refractive index   n20/D 1.444(lit.)
bp   85-90 °C/0.2 mmHg(lit.)
density   0.879 g/mL at 25 °C(lit.)
storage temp.   2-8°C

Description

Packaging

1, 5 g in glass bottle

Application

Di-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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