EMAIL THIS PAGE TO A FRIEND
419419 Sigma-Aldrich

Chitosan

high molecular weight

Synonym: Deacetylated chitin, Poly(D-glucosamine)

Purchase

Properties

Related Categories 3D Printing Materials for Research and Development, Chitosan, Chitosan - Chitosan and Chitin, Chitosan and Chitin, Chitosans (Animal Origin),
Quality Level   100
form   (Coarse ground flakes and powder)
mol wt   310000-375000 Da
viscosity   800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)
solubility   H2O: insoluble
  organic solvents: insoluble
InChI   1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1
InChI key   FLASNYPZGWUPSU-SICDJOISSA-N

Description

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Packaging

50, 250 g in poly bottle

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

>75% deacetylated

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
nwg
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the molecular weight of Chitosan, Product 419419?
Although we do not measure molecular weight on a batch to batch basis, we would expect it to be approximately 310,000 to >375,000 based on the viscosity range of 800-2000 mPaS.
What is the particle size of Product 419419, Chitosan?
The particle size has not been determined.It is described as being course ground flakes or powder.
What is the solubility of Product 419419, Chitosan?
Chitosan is insoluble in water or organic solvents.Hazy suspensions can be prepared in 1M acetic acid at a concentration of 10 mg/mL, but extensive sonication may be required to fully suspend the material.
What is the source of Product 419419, Chitosan?
Chitosan is a natural biopolymer commerically derived from chitin from crustacean shells.
What is the pH of Product 419419, Chitosan?
Our supplier estimates that the pH falls within the range of 6.5-8.0.
What are some uses for chitosan?
Chitosan is a biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery. Please note that Product No. 419419 is for research purposes only, not for cosmetic or drug use.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles

Articles

3D Printing of Carbon Fiber-Reinforced Composites

3D printing is a type of additive manufacturing that can be used to rapidly fabricate components with highly customizable geometries, most typically using a layer-by-layer fabrication process. 3D pri...
Zhenyu Bo* (Ph.D Candidate at Northwestern University) and Jia Choi*, PhD, Product Manager


*Materials Science Product Management Team, MilliporeSigma, Milwaukee, WI.
Keywords: Deposition, Nanomaterials, Nanotubes

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

David Brown,1 Keith Brunt,2 Nils Rehmann3 1CTO Mycodev Group, Fredericton, NB E3B 6B3 Canada 2Dalhousie School of Medicine New Brunswick, Saint John, NB E2K 5E2, Canada 3NiRem Consulting, 8 Fish Hatc...
David Brown, Keith Brunt, Nils Rehmann
Material Matters, 2016, 11.3
Keywords: Antimicrobials, Bacterial conjugations, Cancer, Click chemistry, Clinical, Fermentation, Hemostatics, Pharmaceutical, Titrations

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose. It is the primary, high modulus fibrous component of the exoskeleton of arthropods incl...
Guolin Wu1, Hui Gao2, and Jianbiao Ma1,2
Material Matters, 2012 v7, n3
Keywords: Absorption, Applications, Cell attachment, Cell culture, Degradations, Dialysis, Diseases, Growth factors, Metabolites, Methods, Pharmaceutical, Purification, Renal Disease, Transfection, Vectors

Chitosan: A Versatile Platform for Pharmaceutical Applications

Raphael Riva and Christine Jerome* Center for Education and Research on Macromolecules University of Liege, Chemistry Department, Sart-Tilman, Building B6a, 4000 Liege, Belgium *Email: c.jerome@ulg.a...
Keywords: Acetylations, Adhesion, Aminations, Cancer, Condensations, Coupling reactions, Degradations, Derivatizations, Ethoxylations, Growth factors, Ligands, Pharmaceutical, Polymerization reactions, Precipitation, Reductions, Reductive aminations, Solvents, Substitutions, Transfection

Electrospinning: An Enabling Technique for Nanostructured Materials

Fibrous nanomaterials are attractive for a range of applications due to their intrinsically high porosities and large surface areas. Electrospinning is a simple, versatile technique for generating na...
Dr. Jingwei Xie and Prof. Younan Xia
Material Matters 2008, 3.1, 19.
Keywords: Biomaterials, Cell biology, Central Nervous System, Ceramics, Evaporation, Growth factors, Nanomaterials, Nanotechnology, Nanotubes, Separation, Sol-gel, Stem cell biology

Injectable Hydrogels for Cell Delivery and Tissue Regeneration

Prathamesh M. Kharkar,1 April M. Kloxin1,2* 1Materials Science and Engineering and 2Chemical and Biomolecular Engineering University of Delaware, Newark, DE 19716 USA *Email: akloxin@udel.edu
Keywords: Addition reactions, Adhesion, Angiogenesis, Biochemistry, Biomaterials, Building blocks, Cardiovascular, Catalysis, Cell proliferation, Click chemistry, Clinical, Cycloadditions, Degradations, Growth factors, Reversed-phase chromatography

Microfluidic-Assisted Manufacturing of Materials for Nanomedicine

1Laboratory of Polymers and Biomaterials, Fondazione Istituto Italiano di Tecnologia, 16163, Genova, Italy. 2Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicin...
Keywords: AGE, Biomaterials, Chromatin immunoprecipitation, Clinical, Crystallization, Degradations, Diffusion, Eliminations, Fractionation, Metabolism, Nanomaterials, Pharmaceutical, Precipitation, Reductions, Schizophrenia, Separation, Solvents

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Jiayu Leong,1 Liam Grover,2 Hyunjoon Kong1* 1Department of Chemical and Biomolecular Engineering University of Illinois, Urbana-Champaign, IL 61801 USA 2University of Birmingham, UK *Email: hjkong06@...
Keywords: Adhesion, Adsorption, Aminations, Bacterial conjugations, Biomaterials, Building blocks, Cell culture, Clinical, Deaminations, Degradations, Deposition, Diffusion, Growth factors, Hydroxylations, Immobilization, Ligands, Methylations, Michael reaction, PAGE, Purification, Recombination, Reductive aminations, Transfection

Three-Dimensional Printing of Tissue Engineering Scaffolds

Helena N. Chia, Ph.D.,1* Benjamin M. Wu, D.D.S, Ph.D.1,2* 1Department of Bioengineering, Henry Samueli School of Engineering University of California, Los Angeles, CA 90095 USA 2Division of Advanced ...
Keywords: Biomaterials, Ceramics, Chromatin immunoprecipitation, Deposition, Diagnostic Imaging, Diffusion, Growth factors, Materials Science, Melting, Polymerization reactions, Solvents

Related Content

Chitosan Microparticles

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processin...
Keywords: Acetylations, Microscopy, Scanning electron microscopy

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?