• USA Home
  • 43124 - 1-(Diphenylmethyl)piperazine

EMAIL THIS PAGE TO A FRIEND
43124 Sigma-Aldrich

1-(Diphenylmethyl)piperazine

≥98.0% (NT)

Synonym: 1-Benzhydrylpiperazine

  • CAS Number 841-77-0

  • Empirical Formula (Hill Notation) C17H20N2

  • Molecular Weight 252.35

  •  Beilstein/REAXYS Number 222773

  •  EC Number 212-667-7

  •  MDL number MFCD00038379

  •  PubChem Substance ID 57650151

Purchase

Properties

Related Categories Building Blocks, C16 to C29, Chemical Synthesis, Heterocyclic Building Blocks, Piperazines More...
assay   ≥98.0% (NT)
impurities   ≤5.0% water
SMILES string   C1CN(CCN1)C(c2ccccc2)c3ccccc3
InChI   1S/C17H20N2/c1-3-7-15(8-4-1)17(16-9-5-2-6-10-16)19-13-11-18-12-14-19/h1-10,17-18H,11-14H2
InChI key   NWVNXDKZIQLBNM-UHFFFAOYSA-N

Description

General description

1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes. It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones.

Application

1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.

Packaging

100 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TL6465000
Flash Point(F) 
239 °F
Flash Point(C) 
115 °C

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?