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437018 Sigma-Aldrich

N-Boc-1,6-hexanediamine hydrochloride

97%

Synonym: N-Boc-1,6-diamino-hexane hydrochloride, tert-Butyl N-(6-aminohexyl)carbamate hydrochloride

  • CAS Number 65915-94-8

  • Linear Formula (CH3)3COCONH(CH2)6NH2 · HCl

  • Molecular Weight 252.78

  •  Beilstein/REAXYS Number 3631740

  •  EC Number 265-976-4

  •  MDL number MFCD00039072

  •  PubChem Substance ID 24867340

  •  NACRES NA.22

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Properties

Related Categories Bifunctional Linkers, Building Blocks, Chemical Biology, Chemical Synthesis, Linkers and Crosslinkers,
Quality Level   200
assay   97%
reaction suitability   reagent type: cross-linking reagent
mp   162-164 °C (lit.)
SMILES string   Cl[H].CC(C)(C)OC(=O)NCCCCCCN
InChI   1S/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H
InChI key   JSBWQIZQJOQPFN-UHFFFAOYSA-N

Description

Application

N-Boc-1,6-hexanediamine hydrochloride is a general reagent to introduce a C6-spacer. It can be used in:
• Synthesis of poly(L-glutamic acid) gadolinium chelates as biodegradable MRI contrast agents.
• Synthesis of cholesteryl-functionalized hyaluronic acid-based anionic nanogel for protein delivery.
• Preparation of amphiphilic prodrug, containing anticancer drug chlorambucil, which would self-assemble to form micelles in aqueous solution.

Reagent for the introduction of a C6-spacer.

Packaging

1, 5 g in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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