• USA Home
  • 439320 - 4-(Trifluoromethyl)phenylboronic acid

EMAIL THIS PAGE TO A FRIEND
439320 Sigma-Aldrich

4-(Trifluoromethyl)phenylboronic acid

≥95.0%

Synonym: α,α,α-Trifluoro-p-tolylboronic acid, 4-(Trifluoromethyl)benzeneboronic acid, [p-(Trifluoromethyl)phenyl]boronic acid

  • CAS Number 128796-39-4

  • Linear Formula CF3C6H4B(OH)2

  • Molecular Weight 189.93

  •  Beilstein/REAXYS Number 3544189

  •  MDL number MFCD00151855

  •  PubChem Substance ID 24867498

Purchase

Properties

Related Categories Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids,
InChI Key   ALMFIOZYDASRRC-UHFFFAOYSA-N
assay   ≥95.0%
mp   245-250 °C (lit.)

Description

Application

Reagent used for
• Site-selective Suzuki-Miyaura cross-coupling reactions
• Palladium-catalyzed direct arylation reactions
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
• Ruthenium catalyzed direct arylation
• Ligand-free copper-catalyzed coupling reactions
• Amination and conjugate addition reactions
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions
• Rhodium-catalyzed asymmetric 1,4-addition reactions
• Copper-catalyzed nitration reactions
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation

Reagent used in Preparation of
• Thiazole derivatives for printable electronics
• Terphenyl benzimidazoles as tubulin polymerization inhibitors

Packaging

1, 5 g in glass bottle

Other Notes

Contains varying amounts of anhydride

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Please Enter a Lot Number

Certificate of Origin

Please Enter a Lot Number
Protocols & Articles

Articles

Arylboronic Acids

We are pleased to present its complete selection of arylboronic acids, the building blocks of the Suzuki coupling experiment. Most arylboronic acids readily undergo dehydration reactions to give a cy...
ChemFiles 2001, 1.1, 5.
Keywords: Building blocks, Coupling reactions, Dehydration reaction, Suzuki coupling

Boronic Acids - ChemFiles 2007

Most boronic acids readily undergo dehydration reactions to give a cyclic (trimer) anhydride. Our selection of boronic acids may contain varying amounts of this cyclic anhydride. Fortunately, the aci...
ChemFiles 2007, 7.7, 3.
Keywords: Coupling reactions, Dehydration reaction, Suzuki coupling

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?