441902 Sigma-Aldrich

Cesium carbonate

ReagentPlus®, 99%

Synonym: Carbonic acid dicesium

  • CAS Number 534-17-8

  • Linear Formula Cs2CO3

  • Molecular Weight 325.82

  •  Beilstein/REAXYS Number 4546405

  •  EC Number 208-591-9

  •  MDL number MFCD00010957

  •  PubChem Substance ID 24867711

  •  NACRES NA.22



Related Categories Acids & Bases, Bases, Cesium Salts, Chemical Synthesis, Essential Chemicals,
Quality Level   200
grade   ReagentPlus®
assay   99%
form   powder and chunks
mp   610 °C (dec.) (lit.)
SMILES string   [Cs+].[Cs+].[O-]C([O-])=O
InChI   1S/CH2O3.2Cs/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2


General description

Cesium carbonate is a powerful inorganic base widely used in organic synthesis. It is a potential chemoselective catalyst for the reduction of aldehydes and ketones to alcohols. It is employed as base for the Heck coupling reaction of 4-trifluoromethyl-1-chlorobenzene and aryl chlorides.


Cesium carbonate is an attractive base that finds more and more applications in coupling chemistry.

Cesium carbonate has been employed as catalyst for:
• Aerobic oxidation of primary alcohols.
• 1,4-addition.

Cesium carbonate has been used as reagent for the following studies:
• Synthesis of phosphazene derivatives.
• Constrictive binding interactions.
• Intramolecular C-N cross coupling reactions.
• Dehydohalogenative polycondensation.

Promotes the efficient O-alkylation of alcohols to form mixed alkyl carbonates.


5, 50, 100, 250, 500 g in poly bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is Product 441902, Cesium Carbonate, soluble in?
According to the Merck Index:13th Edition this product is extremely soluble in water and alcohol. It is also soluble in ether.
What are the impurities present in Product 441902, Cesium Carbonate?
We have performed any impurity profiling or testing on this product. However, it has been noted that some of the trace metallic impurities could include, but are not limited to, the following: Lithium, Sodium, Potassium, Rubidium, Aluminum, Barium, Calcium, Chromium, Iron, Magnesium, Nickel, and Silicon.
Product 441902, Cesium Carbonate, is very hygroscopic, how should it be handled in order to preserve the compound?
When we package this product, it is packaged and sealed under a total nitrogen atmosphere to avoid any absorption of water from the atmosphere. It would be optimal to do the same. If you do not have a glove box or glove bagwe do offer Aldrich Atmosbags that can used to help provide an inert atmosphere for compounds such as Cesium Carbonate.One could also flush the head space of the bottle before sealing it to help prevent the material from absorbing moisture during storage.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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Protocols & Articles


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A Single Phosphine Ligand Allows Palladium-Catalyzed Intermolecular C-O Bond Formation with Secondary and Primary Alcohols-

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BrettPhos Ligand Supported Palladium-Catalyzed C-O Bond Formation through an Electronic Pathway of Reductive Elimination: Fluoroalkoxylation of Activated Aryl Halides

A Pd/N-heterocyclic carbene-based catalyst achieves the Sonogashira coupling of an array of functionalized, ?-hydrogen-containing alkyl bromides and iodides under mild conditions. By furnishing the f...
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C-O Cross-Coupling of Activated Aryl and Heteroaryl Halides with Aliphatic Alcohols-

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Cascade Palladium Catalysis: A Predictable and Selectable Regiocontrolled Synthesis of N-Arylbenzimidazoles

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Heck Reaction

The Heck reaction is the palladium catalyzed cross-coupling reaction between alkenes, and aryl or vinyl halides (or triflates) to afford substituted alkenes.1,2 It is a useful carbon–carbon bond form...
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The cross-coupling reaction of aryl bromides and iodides with aliphatic and aromatic thiols catalyzed by palladium complexes of the bisphosphine ligand CyPF-tBu (1) is reported. Reactions occur in ex...
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Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases

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Properties and Applications of Functionalized Graphene Oxide

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Suzuki-Miyaura Cross-Coupling of Potassium Trifluoro(N-methylheteroaryl)borates with Aryl and Heteroaryl Halides

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Synthesis and Application of Palladium Precatalysts that Accommodate Extremely Bulky Di-tert-butylphosphino Biaryl Ligands

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