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457396 Sigma-Aldrich

4-Fluoroindole

97%

  • CAS Number 387-43-9

  • Empirical Formula (Hill Notation) C8H6FN

  • Molecular Weight 135.14

  •  MDL number MFCD00055992

  •  PubChem Substance ID 24869313

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, C7 to C9, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks,
Quality Level   100
assay   97%
bp   90 °C/0.4 mmHg (lit.)
mp   30-32 °C (lit.)
SMILES string   Fc1cccc2[nH]ccc12
InChI   1S/C8H6FN/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5,10H
InChI key   ZWKIJOPJWWZLDI-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
• Reactant for preparation of antifungal agents
• Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
• Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors
• Reactant for preparation of Inhibitors of HIV-1 attachment
• Reactant for preparation of monoamine reuptake inhibitors
• Reactant for preparation of histone deacetylase (HDAC) inhibitors
• Reactant for preparation of inhibitors of proliferation of human breast cancer cells

Packaging

1 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Building blocks, Cardiovascular, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Peer-Reviewed Papers
15

References

Related Products

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