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467006 Sigma-Aldrich

1-Ethynyl-2-fluorobenzene

97%

  • CAS Number 766-49-4

  • Linear Formula FC6H4C≡CH

  • Molecular Weight 120.12

  •  MDL number MFCD00799540

  •  PubChem Substance ID 24870376

  •  NACRES NA.22

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Properties

Related Categories Alkynyl, Alkynyl Fluorinated Building Blocks, Building Blocks, Chemical Synthesis, Fluorinated Building Blocks,
assay   97%
refractive index   n20/D 1.526 (lit.)
bp   150 °C (lit.)
density   1.06 g/mL at 25 °C (lit.)
storage temp.   2-8°C
SMILES string   Fc1ccccc1C#C
InChI   1S/C8H5F/c1-2-7-5-3-4-6-8(7)9/h1,3-6H
InChI key   YFPQIXUNBPQKQR-UHFFFAOYSA-N

Description

General description

1-Ethynyl-2-fluorobenzene, a fluorinated benzene derivative, is a terminal alkyne.

Application

1-Ethynyl-2-fluorobenzene has been employed in the cross-coupling of phenylacetylenes. It may be used in the preparation of 3-(2-deoxy-β-D-ribofuranosyl)-6-(2-fluorophenyl)-2,3-dihydrofuro-[2,3-d]pyrimidin-2-one and 4-(2-fluorophenylethynyl)-3-methyl-5-phenylisoxazole.

Packaging

1 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
UN 1993C 3 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
98.6 °F - closed cup
Flash Point(C) 
37 °C - closed cup

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Peer-Reviewed Papers
15

References

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