• USA Home
  • 470821 - 4-Acetylphenylboronic acid

EMAIL THIS PAGE TO A FRIEND
470821 Sigma-Aldrich

4-Acetylphenylboronic acid

95%

Purchase

Properties

Related Categories Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids,
InChI Key   OBQRODBYVNIZJU-UHFFFAOYSA-N
assay   95%
mp   240-244 °C (lit.)

Description

General description

4-Acetylphenylboronic acid is a boronate, belongs to a class of synthetic organic compounds. It reacts rapidly with peroxynitrite (ONOO(-)) to form stable hydroxy derivatives. It undergoes Suzuki coupling with 4-bromotriphenylamine catalyzed by dichlorobis(triphenylphosphine)Pd(II), during the synthesis of dendrimers.

Application

4-Acetylphenylboronic acid was used in the synthesis of 4′-azidoacetophenone.

Reactant involved in:
• Palladium-catalyzed decarboxylative coupling
• Copper-catalyzed hydroxylation
• Palladium-catalyzed Suzuki-Miyaura cross-coupling
• Cross-coupling with α-bromocarbonyl compounds
• Oxidation catalyzed by Baeyer-Villiger monooxygenases
• 1,5-substitution reactions

Packaging

5, 25 g in glass bottle

Other Notes

Contains varying amounts of anhydride

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Arylboronic Acids

We are pleased to present its complete selection of arylboronic acids, the building blocks of the Suzuki coupling experiment. Most arylboronic acids readily undergo dehydration reactions to give a cy...
ChemFiles 2001, 1.1, 5.
Keywords: Building blocks, Coupling reactions, Dehydration reaction, Suzuki coupling

Boronic Acids - ChemFiles 2007

Most boronic acids readily undergo dehydration reactions to give a cyclic (trimer) anhydride. Our selection of boronic acids may contain varying amounts of this cyclic anhydride. Fortunately, the aci...
ChemFiles 2007, 7.7, 3.
Keywords: Coupling reactions, Dehydration reaction, Suzuki coupling

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?