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471429 Sigma-Aldrich

(S)-(−)-α-Amino-γ-butyrolactone hydrobromide

99%

Synonym: L-Homoserine lactone hydrobromide

  • CAS Number 15295-77-9

  • Empirical Formula (Hill Notation) C4H7NO2 · HBr

  • Molecular Weight 182.02

  •  Beilstein/REAXYS Number 3912375

  •  MDL number MFCD00674493

  •  PubChem Substance ID 24870732

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Lactones, Organic Building Blocks More...
InChI Key   MKLNTBLOABOJFZ-DFWYDOINSA-N
assay   99%
optical activity   [α]20/D −21°, c = 1 in H2O
mp   225 °C (dec.) (lit.)
storage temp.   2-8°C

Description

Application

(S)-(-)-α-Amino-γ-butyrolactone hydrobromide may be used as a building block to prepare:
• β-ketoamide N-acylated-L-homoserine lactones (AHLs) as quorum sensing molecules
• p-coumaroyl-HSL (homoserine lactone)
• calpain and lipid peroxidation inhibitors

Used to prepare pseudopeptide inhibitors for Ras farnesyl-protein transferase as well as selenomethionine.

Packaging

5 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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