• USA Home
  • 473049 - (1S,4S)-(−)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

EMAIL THIS PAGE TO A FRIEND
473049 Sigma-Aldrich

(1S,4S)-(−)-2-Boc-2,5-diazabicyclo[2.2.1]heptane

95%

Synonym: tert-Butyl (1S,4S)-(−)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate

  • CAS Number 113451-59-5

  • Empirical Formula (Hill Notation) C10H18N2O2

  • Molecular Weight 198.26

  •  MDL number MFCD01569250

  •  PubChem Substance ID 24870862

  •  NACRES NA.22

Purchase

Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Other Heterocyclic Building Blocks More...
Quality Level   100
assay   95%
optical activity   [α]22/D −44°, c = 1 in chloroform
mp   74-76 °C (lit.)
SMILES string   CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2
InChI   1S/C10H18N2O2/c1-10(2,3)14-9(13)12-6-7-4-8(12)5-11-7/h7-8,11H,4-6H2,1-3H3/t7-,8-/m0/s1
InChI key   UXAWXZDXVOYLII-YUMQZZPRSA-N

Description

Application

(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane may be used in the preparation of 2-boc-5-(4-nitrophenyl)-2,5-diaza-bicyclo[2.2.1]heptane by reacting with p-nitrobenzene.
It may also be used to develop:
• indazolylpyrazolo[1,5-a]pyrimidine analogs based B-Raf inhibitors
• CCR2 antagonists
• α4β2 nicotinic acetylcholine receptor (nAChR) partial agonists
• azabicyclic sulfonamide based 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors

Packaging

1, 5 g in glass bottle

250 mg in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?