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475629 Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 250

Synonym: PEG diacrylate



Related Categories Acrylate, Bioelectronics, Homobifunctional PEGs, Materials Science, Microfluidics,
Quality Level   100
mol wt   average Mn 250
contains   100 ppm MEHQ as inhibitor
reaction suitability   reagent type: cross-linking reagent
reaction type: Polymerization Reactions
refractive index   n20/D 1.463
density   1.11 g/mL at 25 °C
Ω-end   acrylate
α-end   acrylate
polymer architecture   shape : linear
functionality : homobifunctional
storage temp.   2-8°C
SMILES string   OCCO.OC(=O)C=C
InChI   1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2


General description

Poly(ethylene glycol) diacrylate (PEGDA) is a polyethylene glycol (PEG) based material that can be used for a variety of tissue engineering and drug delivery based applications. It is majorly used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.


PEGDA can be used in the formation of a UV-cured membrane for potential usage in the separation of carbon dioxide (CO2) based gases. It may also be used in the development of novel injectable biodegradable polymers for a variety of biomedical applications.


100, 500 mL in poly bottle

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles


Cell Culture Scaffolds via Bio-orthogonal Click Reactions

1,2Malar A. Azagarsamy, 1Navakanth R. Gandavarapu, 1,2Kristi S. Anseth* 1Department of Chemical and Biological Engineering and 2the Howard Hughes Medical Institute, University of Colorado at Boulder,...
Keywords: Addition reactions, Adhesion, Biomaterials, Catalysis, Cell culture, Cell signaling, Chemical reactions, Click chemistry, Cycloadditions, Degradations, Growth factors, Huisgen Cycloaddition, Ligands, Michael Addition, Peptide synthesis, Polymerization reactions, Step-growth polymerization

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. For decades, research in polymeric biomateria...
Keywords: Absorption, Angiogenesis, Biomaterials, Catalysis, Cell culture, Degradations, Eliminations, Growth factors, Infrared spectroscopy, Ligands, Michael Addition, Polymerization reactions, Ring-opening polymerization

Patterning of PEG-based Hydrogels - Engineering Spatial Complexity

Most biomaterial scaffolds developed for tissue engineering applications are relatively homogeneous and lack the complexity and organization of the in vivo cellular microenvironment. While these homo...
Mariah S. Hahn
Material Matters 2010, 5.3, 62.
Keywords: Absorption, Adhesion, Adsorption, Bacterial conjugations, Biomaterials, Confocal microscopy, Diffusion, Immobilization, Polymerization reactions, Radical polymerization

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers


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