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47624 Sigma-Aldrich

Fmoc-Lys(Boc)-OH

≥98.0% (HPLC)

Synonym: Nα-Fmoc-Nε-Boc-L-lysine

  • CAS Number 71989-26-9

  • Empirical Formula (Hill Notation) C26H32N2O6

  • Molecular Weight 468.54

  •  Beilstein/REAXYS Number 4217767

  •  EC Number 276-256-4

  •  MDL number MFCD00037138

  •  eCl@ss 32160406

  •  PubChem Substance ID 57651044

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Properties

Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Lysine, Peptide Synthesis and Peptide Chemistry,
InChI Key   UMRUUWFGLGNQLI-QFIPXVFZSA-N
assay   ≥98.0% (HPLC)
optical activity   [α]20/D −12±1°, c = 1% in DMF
storage temp.   2-8°C

Description

Application

Fmoc-Lys(Boc)-OH can be used for:
• The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin.
• Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator.
• Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as 19F NMR based screening tool.

Packaging

1, 10, 25 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

Natural Amino Acid Building Blocks for Peptide Synthesis

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.1 Today, the most common synthetic approaches to medium and even large peptide...
Matthias Junkers
ChemFiles 2008, 8.7, 22.
Keywords: Building blocks, Peptide synthesis, Peptidomimetics, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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