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479306 Sigma-Aldrich

cis-Diamineplatinum(II) dichloride

≥99.9% trace metals basis

Synonym: cis-Diammineplatinum(II) dichloride, cis-Dichlorodiammine platinum(II), cis-Platinum(II) diammine dichloride, Cisplatin

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics by Application, Antibiotics by Mechanism of Action, Antineoplastic and Immunosuppressive Antibiotics,
InChI Key   LXZZYRPGZAFOLE-UHFFFAOYSA-L
assay   ≥99.9% trace metals basis
mp   270 °C (lit.)
Mode of action   DNA synthesis | interferes
antibiotic activity spectrum   neoplastics

Description

Biochem/physiol Actions

Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.

Packaging

1, 5, 50 g in glass bottle

Application

cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery.

Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3288 6.1 / PGII
WGK Germany 
3
RTECS 
TP2450000

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How can I get Product 479306,cis-Diammineplatinum(II) dichloride, in solution?
cis-Diammineplatinum(II) dichloride is soluble in water at 25°C. It is also soluble in N,N-dimethylformamide (DMF), dimethylacetamide and dimethyl sulfoxide (DMSO). We do not test solution stability of this product. However, we do have stability data on a document on another cis-Diammineplatinum(II) dichloride product; the product number is P4394.
How should Product 479306, cis-Diammineplatinum(II) dichloride be stored?
This product should be stored at room temperature.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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