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480576 Sigma-Aldrich

6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone

98%

Synonym: 6-Hydroxy-1-tetralone

  • CAS Number 3470-50-6

  • Empirical Formula (Hill Notation) C10H10O2

  • Molecular Weight 162.19

  •  MDL number MFCD00156670

  •  PubChem Substance ID 24871696

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Properties

Related Categories Building Blocks, C10, Carbonyl Compounds, Chemical Synthesis, Ketones,
InChI Key   FNSQPQKPPGALFA-UHFFFAOYSA-N
assay   98%
mp   154-157 °C (lit.)

Description

General description

6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone (6-Hydroxy-1-tetralone) can be prepared by the demethylation of 6-methoxy-3,4-dihydro-1(2H)-naphthalenone. It participates in the synthesis of 2-alkylamino-6-hydroxy-5-hydroxymethyl-1,2,3,4-tetrahydro-1-naphthalenols. Its pKa value has been reported to be 7.74.

Application

6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone (6-Hydroxy-1-tetralone) may be used in the synthesis of:
• 5-chloromethyl-6-hydroxy-3,4-dihydro-1(2H)-naphthalenone
• 6-(4-(3-(piperidin-1-yl)propoxy)benzyloxy)-1-tetralone
• 6-(3-(piperidin-1-yl)propoxy)-1-tetralone

Packaging

5 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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