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481181 Sigma-Aldrich

Silver(I) sulfadiazine


Synonym: Silver sulfadiazine, Sulfadiazine silver



Related Categories Essential Chemicals, Materials Science, Metal and Ceramic Science, Research Essentials, Salts,
Quality Level   100
assay   98%
form   powder
mp   285 °C (dec.) (lit.)
SMILES string   Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2
InChI   1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1



Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.


5, 25 g in glass bottle

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How can Silver sulfadiazine, Product 481181, be dissolved?
Although Sigma-Aldrich does not test the solubility of the silver salt, per the chemicals encyclopedia published by the Royal Society of Chemistry (13th ed.), sulfadiazine is sparingly soluble in water (13mg/100mL at pH 5.5 and 200mg/100mL at pH 7.5), alcohol, and acetone and freely soluble in dilute mineral acids , solutions of potassium and sodium hydroxide, and aqueous ammonium hydroxide.
What can Silver sulfadiazine, Product 481181, be used for?
Although silver sulfadiazine has some potential medical applications, including antibacterial actions and treatment of second and third-degree burns, this product as it is sold is not intended for use with or on humans. Product 481181 is meant for use in research and development purposes only.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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