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512338 Sigma-Aldrich

4-(Hydroxymethyl)phenylboronic acid

≥95%

Synonym: α-Hydroxy-p-tolueneboronic acid, 4-Hydroxymethylbenzeneboronic acid

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Properties

Related Categories Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids,
InChI Key   PZRPBPMLSSNFOM-UHFFFAOYSA-N
assay   ≥95%
mp   251-256 °C (lit.)

Description

Application

Reactant involved in the synthesis of biologically active compounds including:
• Imidazo[4,5-b]pyrazin-2-ones for use as mTOR kinase inhibitors
• Human immunodificiency virus protease inhibitors with activity against resistant viruses

Reactant involved in:
• Suzuki coupling reactions
• Copper-catalyzed transformation from arylboronic acids in water

Involved in the synthesis of polyurethane containing spindle-type chromophores

Packaging

1, 10 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

Arylboronic Acids

We are pleased to present its complete selection of arylboronic acids, the building blocks of the Suzuki coupling experiment. Most arylboronic acids readily undergo dehydration reactions to give a cy...
ChemFiles 2001, 1.1, 5.
Keywords: Building blocks, Coupling reactions, Dehydration reaction, Suzuki coupling

Boronic Acids - ChemFiles 2007

Most boronic acids readily undergo dehydration reactions to give a cyclic (trimer) anhydride. Our selection of boronic acids may contain varying amounts of this cyclic anhydride. Fortunately, the aci...
ChemFiles 2007, 7.7, 3.
Keywords: Coupling reactions, Dehydration reaction, Suzuki coupling

Peer-Reviewed Papers
15

References

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