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518107 Sigma-Aldrich

tert-Butyl 1-indolecarboxylate

97%

Synonym: 1-(tert-Butoxycarbonyl)indole, 1-Indolecarboxylic acid tert-butyl ester, N-tert-Butoxycarbonylindole, N-Butyloxycarbonylindole

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Properties

Related Categories Building Blocks, C13 to C27, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More...
InChI Key   OWPIFQXNMLDXKW-UHFFFAOYSA-N
assay   97%
refractive index   n20/D 1.543 (lit.)
bp   201 °C(lit.)
density   1.07 g/mL at 25 °C (lit.)

Description

Application

Reactant for preparation of:
• Potent plant-growth inhibitors
• Cannabinoid CB2 receptor ligands
• Analogues of isomeridianin G and evaluation as GSK-3β inhibitors
• Inhibitor of the Yersinia pestis salicylate adenylation domain YbtE
• Cholecystokinin-2 receptor antagonists
• Antileishmanial agents

• Reactant for:
• Palladium-catalyzed Suzuki-Miyaura cross coupling reactions
• Friedel-Crafts alkylation reactions

Packaging

25 mL in glass bottle

Safety & Documentation

Safety Information

WGK Germany 
3
Flash Point(F) 
159.8 °F
Flash Point(C) 
71 °C
Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Building blocks, Cardiovascular, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Peer-Reviewed Papers
15

References

Related Products

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