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536954 Sigma-Aldrich

Rosmarinic acid

96%

Synonym: (R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid, 3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester

  • CAS Number 20283-92-5

  • Empirical Formula (Hill Notation) C18H16O8

  • Molecular Weight 360.31

  •  Beilstein/REAXYS Number 2227587

  •  MDL number MFCD00017740

  •  PubChem Substance ID 24878185

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Properties

Related Categories Asymmetric Synthesis, Carboxylic Acids, Cell Biology, Chemical Synthesis, Chiral Building Blocks,
InChI Key   DOUMFZQKYFQNTF-WUTVXBCWSA-N
assay   96%
form   powder
mp   171-175 °C (lit.)
Gene Information   human ... LCK(3932)

Description

General description

Rosmarinic acid is a bioactive plant phenolic compound with antioxidant and anti-inflammatory effects.

Application

Rosmarinic acid has been used as a model compound to study its biological effects in animal models. Various studies have shown its ability to:
• Inhibit nephropathy.
• Inhibit gentamicin sulfate (GS)-induced renal oxidative damage.
• Reduce noise-induced hearing loss.
• Reduce depression.
• Reduce post-traumatic stress disorder (PTSD)-like symptoms.

Packaging

5 g in glass bottle

Biochem/physiol Actions

Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease prevention, kideney disease treatment, cardioprotection and cancer chemoprevention.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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