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544272 Sigma-Aldrich

5-Chlorothiophene-2-sulfonyl chloride

96%

  • CAS Number 2766-74-7

  • Empirical Formula (Hill Notation) C4H2Cl2O2S2

  • Molecular Weight 217.09

  •  MDL number MFCD00051667

  •  PubChem Substance ID 24878721

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Properties

Related Categories Building Blocks, C4 to C6, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks,
InChI Key   SORSTNOXGOXWAO-UHFFFAOYSA-N
assay   96%
refractive index   n20/D 1.586 (lit.)
bp   112-117 °C(lit.)
density   1.623 g/mL at 25 °C (lit.)
storage temp.   2-8°C

Description

General description

5-Chlorothiophene-2-sulfonyl chloride can be prepared from 2-chlorothiophene by reacting with chlorosulfonic acid in the presence of phosphorus pentachloride.

Application

5-Chlorothiophene-2-sulfonyl chloride may be used in the preparation of:
• (S)-N-(5-chlorothiophene-2-sulfonyl)-β,β-diethylalaninol
• N-(3-(1H-pyrazol-1-yl)pyridin-2-yl)-5-chlorothiophene-2-sulfonamide
• 5-chloro-4-nitrothiophene-2-sulfonyl chloride

Packaging

1, 5 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3265 8 / PGII
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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