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549207 Sigma-Aldrich

5-Amino-3-(4-methylphenyl)pyrazole

97%

Synonym: 3-Amino-5-(4-methylphenyl)-1H-pyrazole

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Properties

Related Categories Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Pyrazoles More...
InChI Key   GVPFRVKDBZWRCZ-UHFFFAOYSA-N
assay   97%
mp   148-151 °C (lit.)

Description

Packaging

5 g in glass bottle

Application

5-Amino-3-(4-methylphenyl)pyrazole may be used:
• As a starting material for preparing 2,5-bis(4-methylphenyl)-7-phenyl-6,7-dihydropyrazolo[1,5-a]pyrimidine-3,6-dicarbaldehyde, a potential precursor for building bioactive fused polycyclic pyrazoles.
• To synthesize 4-hetarylpyrazolo[1,5-a][1,3,5]triazines under microwave conditions and in the absence of solvent.
• To synthesize 5-cyano-6,7-dihydro-3-(4-methylphenyl)-6-oxo-1H-pyrazolo[3,4-b]pyridine-4-carboxylates by reacting with dialkyl dicyanofumarates.

General description

5-Amino-3-(4-methylphenyl)pyrazole or 5-amino-3-(4-methylphenyl)-1H-pyrazole belongs to a family of 5-aminopyrazole derivatives, which are bioactive agents. They find a wide range of applications in the pharmaceutical and agrochemical industries.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

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Protocols & Articles
Peer-Reviewed Papers
15

References

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