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549606 Sigma-Aldrich

2′-Aminoacetanilide

98%

Synonym: N-(2-Aminophenyl)acetamide, o-Aminoacetanilide

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Properties

Related Categories Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Protected Amines More...
InChI Key   MPXAYYWSDIKNTP-UHFFFAOYSA-N
assay   98%
mp   133-137 °C (lit.)

Description

Packaging

5, 25 g in glass bottle

Application

2′-Aminoacetanilide may be used in the preparation of:
• 2-Methylbenzimidazole.
• N-(2-(1,3-Dimethyl-2,4-dioxo-5-phenyl-3,4-dihydro-1H-pyrrolo[3,4-d]pyrimidin-6(2H)-yl)phenyl)-5-methylfuran-2-carboxamide, a potent cystic fibrosis transmembrane conductance regulator (CFTR) inhibitor.
• Azobenzothiazole dyes, N-[2-(6-nitrobenzothiazol-2-ylazo)phenyl]acetamide and N-[2-(benzothiazol-2-ylazo)phenyl]acetamide.

General description

2′-Aminoacetanilide (2-aminoacetanilide, o-aminoacetanilide) can be prepared by the catalytic hydrogenation of 2-nitroacetanilide using 10%Pd/C (palladium/carbon).

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

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Protocols & Articles
Peer-Reviewed Papers
15

References

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