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556327 Sigma-Aldrich

4-Bromophenyl methyl sulfone

97%

Synonym: 1-Bromo-4-(methylsulfonyl)benzene

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Properties

Related Categories Building Blocks, Chemical Synthesis, Organic Building Blocks, Sulfones - Sulfur Compounds, Sulfur Compounds More...
InChI Key   FJLFSYRGFJDJMQ-UHFFFAOYSA-N
assay   97%
mp   103-107 °C (lit.)

Description

Application

4-Bromophenyl methyl sulfone may be used to synthesize:
• biaryl methyl sulfones
• 5-[[-4-(methylsulfonyl)phenyl]thio]thiophene-2-sulfonamide
• 1-[4-(methylsulfonyl)phenyl]-1H-pyrazole (Hmsppz)
• DuP 697 via reaction with (5-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)trimethylsilane

4-Bromophenyl methyl sulfone (1-bromo-4-(methylsulfonyl)benzene) can undergo coupling reaction with benzene sulfonamide in the presence of copper(I)iodide to form the corresponding N-aryl sulfonamide.

Packaging

5, 25 g in glass bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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