EMAIL THIS PAGE TO A FRIEND
578797 Sigma-Aldrich

3-Ethynylthiophene

96%

Purchase

Properties

Related Categories Building Blocks, C4 to C6, Chemical Synthesis, Heterocyclic Building Blocks, Thiophenes More...
InChI Key   MJHLPKWONJUCFK-UHFFFAOYSA-N
assay   96%
refractive index   n20/D 1.5800(lit.)
bp   152-153 °C(lit.)
density   1.098 g/mL at 25 °C(lit.)

Description

Packaging

1, 5 g in glass bottle

Application

3-Ethynylthiophene may be used in the synthesis of the following:
• 1-(2-bromobenzyl)-4-(thiophen-3-yl)-1H-1,2,3-triazole which is obtained by heating with 2-iodophenylethylazide in the presence of copper acetate monohydrate catalyst in N-methyl-2-pyrrolidone
• N-benzyl-1-phenyl-5-(thiophen-3-yl)-4-pentyn-2-amine via a multi-step reaction process
• [(C4H3S-3)C≡CAg]n, a polymeric compound obtained via reaction with silver nitrate in the presence of triethylamine in acetonitrile
• 4,5-bis(thiophen-3-ylethynyl)phthalonitrile via Sonogashira cross-coupling reaction with 4,5-dichlorophthalonitrile

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1993C 3 / PGIII
WGK Germany 
3
Flash Point(F) 
114.8 °F
Flash Point(C) 
46 °C

Meet Synthia - Retrosynthesis Sofware
Protocols & Articles

Articles

New Aromatic Terminal Alkynes

The terminal alkyne functionality has a wide range of applications including most recently the synthesis of spiropyran substituted 2,3-dicyanopyrazines1 and (±)-asteriscanolide,2 as well as conversio...
Chemfiles Volume 3 Article 5
Keywords: Applications, Medicinal chemistry, Organic synthesis

Related Content

Alkynes and Acetylenic Building Blocks

We list over 600 alkyne building blocks, including a wide array of propargyl alcohols, acetylenic boron reagents, and halogenated substrates for cross-coupling. Additionally, many of these are termin...
Keywords: Building blocks, Coupling reactions, Cross couplings

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?