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632414 Sigma-Aldrich

Indole-7-carboxaldehyde

97%

Synonym: 7-Formylindole

  • CAS Number 1074-88-0

  • Empirical Formula (Hill Notation) C9H7NO

  • Molecular Weight 145.16

  •  MDL number MFCD01318152

  •  PubChem Substance ID 24882324

  •  NACRES NA.22

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Properties

Related Categories Aldehydes, Building Blocks, C7 to C9, C9, Carbonyl Compounds,
InChI Key   XQVZDADGTFJAFM-UHFFFAOYSA-N
assay   97%
mp   87-91 °C (lit.)

Description

Application

• reactant for preparation of antiandrogens
• reactant for preparation of antiplatelet agent
• reactant for preparation of liver X receptor (LXR) agonists
• reactant for preparation of antagonists of the EP3 receptor for prostaglandin E2
• reactant for preparation of inhibitors of glycoprotein perforin
• reactant for preparation of potent antitubulin agents
• reactant for preparation of potential insulin receptor activators
• reactant for preparation of potential scaffolds for peptide mimetics
• reactant for preparation of 5-Hydroxytryptamine1D receptor antagonist
• reactant for preparation of indolocarbazole kinase inhibitors

Used in an efficient synthesis of fused pyrroloquinolinedicarboxylates from acetylenedicarboxylates and triphenylphosphine.

Packaging

1, 5 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Indoles

Sigma-Aldrich is proud to offer a new series of ChemFiles—called Privileged Structures, to our Drug Discovery and Organic Synthesis customers. Each piece will highlight a specific motif, selected app...
Chemfiles Volume 4 Article 8
Keywords: Building blocks, Cardiovascular, Diabetes, Diseases, Drug discovery, Medicinal chemistry, Organic synthesis, Respiratory

Peer-Reviewed Papers
15

References

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